The unsuspected source of oxygen in Crohn´s Disease

Original Article

Abstract

Crohn disease is a chronic idiopathic inflammatory bowel disease condition characterized by skip lesions and transmural inflammation that can affect the entire gastrointestinal tract from the mouth to the anus.  Presenting symptoms are often variable and may include diarrhea, abdominal pain, weight loss, nausea, vomiting, and in certain cases fevers or chills.  in some cases, extraintestinal manifestations may develop. The diagnosis is typically made with endoscopic and/or radiologic findings. Disease management is usually with pharmacologic therapy; however, most patients will eventually require surgery for their disease.

Crohn disease can affect any part of the gastrointestinal tract. About one-third of patients have small bowel involvement, especially the terminal ileum, another 20% have only colon involvement and about 50% be involved of both the colon and small bowel. So far, there is no cure, and most patients experience bouts of remissions and relapse at unpredictable times. This disease leads to very poor quality of life.

Our observation that our body does not take oxygen from the air, but from intracellular water, like plants, implies rethinking the etiopathogenesis of the disease. Crohn's disease, because until now, the interpretation of clinical findings is because we take oxygen from the air, when the purpose of breathing is only to expel the CO₂ that is continually formed inside our body.