Vitamin A Treatment for Recurrent Urinary Tract Infections in a Post-Roux-en-Y Gastric Bypass Patient: A Case Report

Case Report


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Authors

  • Adel Ekladious

DOI:

https://doi.org/10.58372/2835-6276.1235

Abstract

This case describes a 35-year-old female who developed recurrent urinary tract infections (UTIs) after Roux-en-Y gastric bypass surgery. Cystoscopy and biopsy revealed severe keratinizing desquamative squamous metaplasia (KDSM) of the urinary tract. Further evaluation uncovered deficiencies in vitamins A, D, and E, with vitamin A deficiency suspected as the primary contributor to urinary symptoms and night blindness. High-dose vitamin A supplementation, along with other micronutrients, resolved both urinary and visual symptoms, and follow-up cystoscopy showed restoration of healthy epithelium. This case highlights the importance of comprehensive micronutrient assessment in post-bariatric patients with recurrent UTIs.

References

SAGES Surgery. Guidelines for Clinical Application of Laparoscopic Bariatric Surgery - A SAGES Publication. SAGES. 2013.

Fried M, Yumuk V, Oppert JM, Scopinaro N, Torres AJ, Weiner R, et al. Interdisciplinary European Guidelines on Metabolic and Bariatric Surgery. Obesity Facts. 2013; 6:449–68.

Salameh BS, Khoukaz MT, Bell RL. Metabolic and nutritional changes after bariatric surgery. Expert Review of Gastroenterology & Hepatology. 2010 Apr; 4:217–23.

Lange J, Königsrainer A. Malnutrition as a Complication of Bariatric Surgery – A Clear and Present Danger? Visceral Medicine. 2019; 35:305–11.

Mohapatra S, Gangadharan K, Pitchumoni CS. Malnutrition in obesity before and after bariatric surgery. Disease-a-Month. 2020 Feb;66(2):100866.

WHO. Nutritional anaemias: tools for effective prevention and control. www.who.int. 2017. ‌

Smelt HJM, Pouwels S, Smulders JF, Hazebroek EJ. Patient adherence to multivitamin supplementation after bariatric surgery: a narrative review. Journal of Nutritional Science. 2020;9.

National Research Council (US) Subcommittee on the Tenth Edition of the Recommended Dietary Allowances. Fat-Soluble Vitamins. Nih.gov. National Academies Press (US); 2018.

Saeed A, Hoekstra M, Hoeke MO, Heegsma J, Faber KN. The interrelationship between bile acid and vitamin A homeostasis. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids. 2017 May; 1862:496–512.

Lumen Learning. Chemical Digestion and Absorption: A Closer Look | Anatomy and Physiology II. Lumenlearning.com. 2019.

McCullough FSW, Northrop-Clewes CA, Thurnham DI. The effect of vitamin A on epithelial integrity. Proceedings of the Nutrition Society. 1999 May; 58:289–93.

Wang JL, Swartz-Basile DA, Rubin DC, Levin MS. Retinoic Acid Stimulates Early Cellular Proliferation in the Adapting Remnant Rat Small Intestine after Partial Resection. The Journal of Nutrition. 1997 Jul 1;127 :1297–303.

Amit-Romach E, Uni Z, Cheled S, Berkovich Z, Reifen R. Bacterial population and innate immunity-related genes in rat gastrointestinal tract are altered by vitamin A-deficient diet. The Journal of Nutritional Biochemistry. 2009 Jan 1; 20:70–7. ‌

Surman SL, Penkert RR, Sealy RE, Jones BG, Marion TN, Vogel P, et al. Consequences of Vitamin A Deficiency: Immunoglobulin Dysregulation, Squamous Cell Metaplasia, Infectious Disease, and Death. International Journal of Molecular Sciences. 2020 Aug 4;21 :5570.

Takahashi Y, Miura T, Takahashi K. Vitamin A is Involved in Maintenance of Epithelial Cells on the Bronchioles and Cells in the Alveoli of Rats. Journal of Nutrition. 1993 Apr 1; 123:634–41.

García OP. Effect of vitamin A deficiency on the immune response in obesity. Proceedings of the Nutrition Society. 2012 Feb 28; 71:290–7.

Sammer U, Walter M, Knüpfer SC, Mehnert U, Bode-Lesniewska B, Kessler TM. Do We Need Surveillance Urethro-Cystoscopy in Patients with Neurogenic Lower Urinary Tract Dysfunction? PLOS ONE. 2015 Oct 29; 10: e0140970–0.

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Published

2024-11-30

How to Cite

Adel Ekladious. (2024). Vitamin A Treatment for Recurrent Urinary Tract Infections in a Post-Roux-en-Y Gastric Bypass Patient: A Case Report: Case Report. American Journal of Medical and Clinical Research & Reviews, 3(11), 1–6. https://doi.org/10.58372/2835-6276.1235

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