Persistent pyrosis revealing generalized myasthenia gravis: Case Report

Bachir Mansour Diallo

doi:10.58372/2835-6276.1209

Authors

Bachir Mansour Diallo

DOI:

https://doi.org/10.58372/2835-6276.1209

Keywords:

digestive disorders, myasthenia, auto-immune

Abstract

Introduction: Autoimmune myasthenia gravis is a condition associated with autoimmune disruption of neuromuscular transmission. Digestive manifestations are common, but lead to misdiagnosis.

Observation : An 18-year-old female with no specific pathological history was treated for gastroesophageal reflux disease (GERD) with persistent pyrosis and ulcerative epigastralgia, which prompted several consultations. An oesogastroduodenal transit revealed oesophageal dilatation with stage, and fibroscopy confirmed oesophageal dilatation and the presence of erythematous antral gastritis. In the internal medicine consultation, she presented with motor deficit in all 4 limbs and a waddling gait. Biological tests revealed positive anti-choline acetyl receptor antibodies. The electroneuromyogram suggested generalized myasthenia. We noted a good clinical course with symptomatic treatment of digestive disorders, pyridostigmine and conventional immunosuppressants.

Conclusion: Digestive disorders can complicate generalized myasthenia. They should prompt a holistic diagnostic approach for better patient management.

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