Hyperbaric Therapy “Long Life Oxy-Lord” As New Protocol Facing the Oxidative Stress associated with metabolic imbalance such as Neurodegenerative and Cancer diseases

Research Article

Abstract

Motor neuron diseases (MNDs) are progressive neurological disorders that affect motor neurons, such as amyotrophic lateral sclerosis (ALS), which can cause rapid loss of muscle control and paralysis. Although there is currently no definitive cure, new treatments are being developed, including epigenetic therapies. Hyperbaric oxygen therapy has emerged as an innovative strategy within this category, demonstrating its ability to restore biological processes involved in mitochondrial renewal and slow the progression of MNDs. Humans act as natural hyperbaric chambers, regulating their internal pressure through oxygen combustion, and this internal pressure must be balanced with external pressure to ensure optimal energy flow between the individual and their environment. To maximize the effectiveness of interventions such as hyperbaric oxygen therapy, understanding individual genetic variability is crucial. Genetic polymorphism analyses, which represent the most precise and advanced method for identifying specific genetic variations, are essential for understanding how these variations affect the individual's response to oxidative stress and alterations in energy production. These analyses allow for the personalization of critical oxygen doses (CDO) and the adaptation of therapy protocols to the patient’s specific genetic needs, thereby optimizing treatment outcomes with epigenetic therapies, among which oxygen therapy is essential. We have developed the LONGLIFE OXY-LORD algorithm, which adjusts the pressure in the hyperbaric chamber based on factors such as body size and cranial, thoracic, and abdominal morphology. This algorithm correlates the individual's morphology with their pathophysiology to estimate the CDO, which is crucial for ensuring adequate oxygen flow. Integrating genetic polymorphism analyses into this methodology would allow for a more precise estimation of the CDO, considering how individual genetic variations influence the body's ability to handle oxidative stress. We propose using probiotics as oxygen carriers and aerobic microorganisms as fixators and evaluate how oxygen contributes to metabolic activation and neurotransmitter transmission through damaged neural connections. Additionally, olive oil is used to protect these circuits from further damage. Integrating genetic polymorphism analyses into hyperbaric therapy and the “Long Life Oxy-Lord” protocol has the potential to significantly enhance the therapeutic approach to Oxidative stress associated with metabolic imbalance against neurodegenerative and cancer diseases, enabling more personalized and effective treatments.