Use of Artificial Intelligence in the Diagnosis of Ocular Diseases: An Article Review
Review Article


DOI:
https://doi.org/10.58372/2835-6276.1306Keywords:
Artificial Intelligence, Ocular Diagnosis, Diabetic Retinopathy, Machine Learning, OphthalmologyAbstract
Artificial intelligence (AI) has established itself as a transformative tool in ophthalmic practice, especially for the early diagnosis of diabetic retinopathy, glaucoma and age‑related macular degeneration (AMD). Convolutional neural networks trained on large retinal‑image databases have demonstrated accuracy comparable to—and in some scenarios surpassing—that of human specialists, enabling large‑scale screening at reduced cost and with broader reach of care. Besides expanding access in regions lacking ophthalmologists, AI reduces inter‑observer variability and streamlines routine examinations, freeing clinicians to focus on complex cases. Over recent decades, collaborative efforts among universities, technology companies and health‑care services have produced algorithms that integrate clinical data and electronic health records to generate personalised risk predictions and therapeutic recommendations. Nevertheless, algorithmic bias, the scarcity of representative datasets and regulatory hurdles still constrain widespread adoption of these solutions. We conclude that, although AI is already clinically useful in specific contexts, continuous validation, transparency and medical education are essential for the technology to realise its full potential in combating preventable blindness.
References
ABRÀMOFF, M. D. et al. Automated analysis of retinal imaging using machine learning for diabetic retinopathy screening. Ophthalmology, 2020.
BURLINA, P. M. et al. Detecting age‑related macular degeneration via deep learning. JAMA Ophthalmology, 2019.
DE FAUW, J. et al. Clinically applicable deep learning for diagnosis and referral in retinal disease. Nature Medicine, 2018.
GRASSMANN, F. et al. Predicting age‑related macular degeneration using AI‑based retinal imaging analysis. Retina, 2019.
GULSHAN, V. et al. Development and validation of a deep learning algorithm for detection of diabetic retinopathy in retinal fundus photographs. JAMA, 2018.
KEEL, S. et al. Visualizing the impact of deep learning models for retinal disease detection. Nature Biomedical Engineering, 2019.
LEE, C. S. et al. Deep learning for automated diagnosis of retinal diseases. Investigative Ophthalmology & Visual Science, 2018.
LI, Z. et al. AI in screening for ocular diseases. BMJ Open Ophthalmology, 2020.
LIU, X. et al. Machine learning approaches for diagnosing glaucoma. Journal of Medical AI Research, 2021.
NARAYANASWAMY, A. et al. Artificial intelligence and optical coherence tomography. American Journal of Ophthalmology, 2020.
RAJALAKSHMI, R. et al. Automated diabetic retinopathy detection in teleophthalmology. Journal of Telemedicine and Telecare, 2018.
SCHMIDT‑ERFURTH, U. et al. AI and telemedicine in ophthalmology. European Journal of Ophthalmology, 2021.
TING, D. S. W. et al. Deep learning in ophthalmology: technical and clinical considerations. Progress in Retinal and Eye Research, 2019.
TING, D. S. W. et al. Future applications of AI in ophthalmology. Nature Digital Medicine, 2021.
YIM, J. et al. Predicting systemic health conditions from retinal images. Nature Biomedical Engineering, 2020.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 American Journal of Medical and Clinical Research & Reviews

This work is licensed under a Creative Commons Attribution 4.0 International License.